LAWSON08-III non-contact ultrasonic processors, also known as gene disruptor, is often used for aseptic fragmentation. It can break chromosomes and break cells through a centrifuge tube. The device with silencer is especially used for the release of adenovirus particles. In addition to being suitable for preparing high-titer recombinant adenovirus, it can also prepare viral DNA and DNA terminal protein compounds, and is an ideal instrument for soil sample preparation. It has become an indispensable standardization tool for CHIP (chromatin immunoprecipitation) research platforms. Non-contact ultrasonic cell pulverizer, also known as ultrasonic cell pulverizer, is suitable for reaction systems with special needs. Compared with traditional contact ultrasonic methods, it has outstanding performance in terms of safety, precision, reaction efficiency, reaction boundary conditions and reaction uniformity. The advantages. Non-contact ultrasonic cell pulverizers are widely used, mainly for cell disruption, lysis and release of cell content particles.

Multiple samples can be detected at one time, with high experimental efficiency; no wear and slag removal, each sample is in a separate fully enclosed test tube to avoid cross-contamination; optional cooling water circulation system, which is convenient for samples to be ultrasonicated in a 4 ℃ water bath, energy The distribution is uniform and the ultrasonic effect is complete; the ultrasonic parameter setting is flexible, the experimental steps are standardized, the experiment repeatability is good, and the results are highly reliable.

It has gradually become an indispensable standardized tool for ChIP (chromatin immunoprecipitation) and DNA shearing research platforms. It has high experimental efficiency, reliable results, and good repeatability. It can process a minimum of 5ul samples and is suitable for precious samples.

The working principle of non-contact ultrasonic processors:

    The non-contact ultrasonic processors (Ultrasonic Cell Crusher) adopts the design of installing an ultrasonic generating device at the bottom of the water tank. In traditional probe ultrasonic pulverizers, the micro-flow phenomenon caused by ultrasonic waves can only occur in the area close to the probe. The ultrasonic cell crusher is equipped with an ultrasonic generator at the bottom of the water tank, so that the water tank is completely within the action range of ultrasonic waves, and the ultrasonic action is widely distributed and balanced, which reduces the formation of foam. During the experiment, the non-contact ultrasonic cell pulverizer automatically and continuously rotates the centrifuge tube to make the ultrasonic power distribution more uniform. The non-contact ultrasonic cell pulverizer is in the middle of the experimental process. The samples are placed in independent fully sealed centrifuge tubes, and there is no cross-contamination between samples, which avoids the spread of aerosols.

Advantages of non-contact ultrasonic processors:

   In the traditional Ultrasonic Cell Crusher, the probe is in direct contact with the sample, and there is metal ion contamination. Only one sample can be processed at a time, and the experimental period is long; for multiple samples, the same probe needs to be reused, which is easy to cause cross-contamination of samples. Since the depth of the probe inserted into the sample is different each time, the energy distribution of each ultrasonic wave is also different, which affects the repeatability and accuracy of the experimental results. In addition, since a closed system cannot be used, the aerosol or foam generated during the ultrasound process can diffuse into the environment, creating a potential biohazard. The non-contact ultrasonic cell crusher can detect 4-32 samples at a time, with high experimental efficiency; no need to operate the probe frequently, each sample is in a separate fully enclosed test tube to avoid cross-contamination; 4-degree water bath, ultrasonic energy distribution Uniform and complete ultrasonic effect; flexible ultrasonic parameter settings, standardized experimental steps, good experimental repeatability, and high reliability of results.

⒈ No aerosol aerosol production - enhanced biological safety (such as mycobacteria, viruses, etc.)

⒉ Eliminates the risk of cross-contamination of samples

⒊ Eliminate the phenomenon of traditional probe wear and slag

⒋Can handle a variety of samples, a wide range of sample processing

⒌Applicable to various standard containers

⒍Can be used to process micro samples, the minimum is 5ul

⒎The automatic continuous rotation of the centrifuge tube makes the energy distribution of the ultrasonic wave more uniform

⒏ Optional high and low temperature constant temperature water bath, customized Eppendorf tube crushing rotating base of various diameters according to customer requirements

Application range:

⒈ DNA fragmentation

⒉ RNA fragmentation

⒊Bacteria and cell disruption

⒋ChIp assay (chromatin immunoprecipitation)

⒌Sample pretreatment for high-throughput sequencer

⒍ Take membrane protein

⒎ Homogenization, emulsification reaction

⒏ Ultrasonic treatment of precious reagents

non-contact ultrasonic processors LAWSON08-II advantage：

In closed systems, the aerosol or foam generated during sonication can diffuse into the environment, creating a potential biohazard. The non-contact automatic ultrasonic crusher can detect 4-32 samples at a time, with high experimental efficiency; no need to operate the probe frequently, each sample is in a separate fully enclosed test tube to avoid cross-contamination; ultrasonic energy distribution is uniform, and ultrasonic effect Complete; flexible ultrasonic parameter settings, standardized experimental steps, good experimental repeatability, and high reliability of results.

Main features of non-contact ultrasonic processors LAWSON08-III:

[1]Large-screen LCD display, optional 7-inch touch screen control.

[2] It can detect 4 to 32 samples at the same time in a single time, and the experimental efficiency is high.

[3] Closed system to avoid cross-contamination and high safety.

[4]Multiple sample processing, wide application range.

[5]It can effectively prevent the generation of sample foam.

[6]The interface of cooling water circulation device is optional, and the low temperature cooling liquid circulation machine is optional.

[7]Optional RS485 or RS232 communication interface

Non-contact ultrasonic crushing application range

⒈ DNA fragmentation

⒉RNA Fragmentation

⒊Bacteria and cell disruption

⒋ChIp assay (chromatin immunoprecipitation)

⒌Pretreatment of high-throughput sequencer samples

⒍Take membrane protein

⒎ Homogenization, emulsification reaction

⒏ Ultrasonic treatment of precious reagents

Precautions before use:

1. Select the appropriate probe according to the sample volume to be processed, and the probe must be replaced with a special wrench;

2. When the AMPLITUDE knob is turned on, the probe must not be exposed to the air, and in special cases (test probe) should not exceed 10 seconds;

3. Prepare an ice box before use, and the sample must be placed in an ice bath during processing, and the sample concentration should not be too large.

LAWSON08-III non-contact ultrasonic processors, also known as gene disruptor, is often used for aseptic fragmentation. It can break chromosomes and break cells through a centrifuge tube. The device with silencer is especially used for the release of adenovirus particles. In addition to being suitable for preparing high-titer recombinant adenovirus, it can also prepare viral DNA and DNA terminal protein compounds, and is an ideal instrument for soil sample preparation. It has become an indispensable standardization tool for CHIP (chromatin immunoprecipitation) research platforms. Non-contact ultrasonic cell pulverizer, also known as ultrasonic cell pulverizer, is suitable for reaction systems with special needs. Compared with traditional contact ultrasonic methods, it has outstanding performance in terms of safety, precision, reaction efficiency, reaction boundary conditions and reaction uniformity. The advantages. Non-contact ultrasonic cell pulverizers are widely used, mainly for cell disruption, lysis and release of cell content particles.